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Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer

JOURNAL ARTICLE published January 2015 in Cancer Cell

Authors: Carlotta Costa | Hiromichi Ebi | Miriam Martini | Sean A. Beausoleil | Anthony C. Faber | Charles T. Jakubik | Alan Huang | Youzhen Wang | Madhuri Nishtala | Ben Hall | Klarisa Rikova | Jean Zhao | Emilio Hirsch | Cyril H. Benes | Jeffrey A. Engelman

https://doi.org/10.1016/j.ccell.2014.11.007 Actions

A Conditional Mouse Model for Malignant Mesothelioma

JOURNAL ARTICLE published March 2008 in Cancer Cell

Authors: Johan Jongsma | Erwin van Montfort | Marc Vooijs | John Zevenhoven | Paul Krimpenfort | Martin van der Valk | Marc van de Vijver | Anton Berns

https://doi.org/10.1016/j.ccr.2008.01.030 Actions

Drugging MYCN through an Allosteric Transition in Aurora Kinase A

JOURNAL ARTICLE published September 2014 in Cancer Cell

Authors: William Clay Gustafson | Justin Gabriel Meyerowitz | Erin A. Nekritz | Justin Chen | Cyril Benes | Elise Charron | Erin F. Simonds | Robert Seeger | Katherine K. Matthay | Nicholas T. Hertz | Martin Eilers | Kevan M. Shokat | William A. Weiss

https://doi.org/10.1016/j.ccr.2014.07.015 Actions

Integrin β4 signaling promotes tumor angiogenesis

JOURNAL ARTICLE published November 2004 in Cancer Cell

Authors: Sotiris N. Nikolopoulos | Pamela Blaikie | Toshiaki Yoshioka | Wenjun Guo | Filippo G. Giancotti

https://doi.org/10.1016/j.ccr.2004.09.029 Actions

X chromosomal abnormalities in basal-like human breast cancer

JOURNAL ARTICLE published February 2006 in Cancer Cell

Authors: Andrea L. Richardson | Zhigang C. Wang | Arcangela De Nicolo | Xin Lu | Myles Brown | Alexander Miron | Xiaodong Liao | J. Dirk Iglehart | David M. Livingston | Shridar Ganesan

https://doi.org/10.1016/j.ccr.2006.01.013 Actions

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

JOURNAL ARTICLE published October 2011 in Cancer Cell

Authors: Nu Zhang | Ping Wei | Aihua Gong | Wen-Tai Chiu | Hsueh-Te Lee | Howard Colman | He Huang | Jianfei Xue | Mingguang Liu | Yong Wang | Raymond Sawaya | Keping Xie | W.K. Alfred Yung | René H. Medema | Xi He | Suyun Huang

https://doi.org/10.1016/j.ccr.2011.08.016 Actions

Molecular classification and diagnostics of upper urinary tract urothelial carcinoma

JOURNAL ARTICLE published June 2021 in Cancer Cell

Authors: Yoichi Fujii | Yusuke Sato | Hiromichi Suzuki | Nobuyuki Kakiuchi | Tetsuichi Yoshizato | Andrew T. Lenis | Shigekatsu Maekawa | Akira Yokoyama | Yasuhide Takeuchi | Yoshikage Inoue | Yotaro Ochi | Yusuke Shiozawa | Kosuke Aoki | Kenichi Yoshida | Keisuke Kataoka | Masahiro M. Nakagawa | Yasuhito Nannya | Hideki Makishima | Jimpei Miyakawa | Taketo Kawai | Teppei Morikawa | Yuichi Shiraishi | Kenichi Chiba | Hiroko Tanaka | Genta Nagae | Masashi Sanada | Eiji Sugihara | Taka-Aki Sato | Tohru Nakagawa | Masashi Fukayama | Tetsuo Ushiku | Hiroyuki Aburatani | Satoru Miyano | Jonathan A. Coleman | Yukio Homma | David B. Solit | Haruki Kume | Seishi Ogawa

https://doi.org/10.1016/j.ccell.2021.05.008 Actions

The translational challenges of precision oncology

JOURNAL ARTICLE published May 2022 in Cancer Cell

Authors: Oriol Pich | Chris Bailey | Thomas B.K. Watkins | Simone Zaccaria | Mariam Jamal-Hanjani | Charles Swanton

https://doi.org/10.1016/j.ccell.2022.04.002 Actions

Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis

JOURNAL ARTICLE published November 2017 in Cancer Cell

Authors: Anh Tuan Nguyen | Joanne Chia | Manon Ros | Kam Man Hui | Frederic Saltel | Frederic Bard

https://doi.org/10.1016/j.ccell.2017.10.001 Actions

SnapShot: Hepatocellular Carcinoma

JOURNAL ARTICLE published April 2014 in Cancer Cell

Authors: Jens U. Marquardt | Snorri S. Thorgeirsson

https://doi.org/10.1016/j.ccr.2014.04.002 Actions

Clinical Challenges of Immune Checkpoint Inhibitors

JOURNAL ARTICLE published September 2020 in Cancer Cell

Authors: Maria de Miguel | Emiliano Calvo

https://doi.org/10.1016/j.ccell.2020.07.004 Actions

VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium

JOURNAL ARTICLE published February 2012 in Cancer Cell

Authors: Tara Karnezis | Ramin Shayan | Carol Caesar | Sally Roufail | Nicole C. Harris | Kathryn Ardipradja | You Fang Zhang | Steven P. Williams | Rae H. Farnsworth | Ming G. Chai | Thusitha W.T. Rupasinghe | Dedreia L. Tull | Megan E. Baldwin | Erica K. Sloan | Stephen B. Fox | Marc G. Achen | Steven A. Stacker

https://doi.org/10.1016/j.ccr.2011.12.026 Actions

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation

JOURNAL ARTICLE published May 2004 in Cancer Cell

Authors: Sari Kurki | Karita Peltonen | Leena Latonen | Taija M Kiviharju | Päivi M Ojala | David Meek | Marikki Laiho

https://doi.org/10.1016/s1535-6108(04)00110-2 Actions

The Multifaceted Role of Perivascular Macrophages in Tumors

JOURNAL ARTICLE published July 2016 in Cancer Cell

Research funded by Cancer Research UK (C11712/A13028) | Yorkshire Cancer Research (S382) | NIH (CA172451,CA100324) | Wellcome Trust (101067/Z/13/Z) | Medical Research Council (G1002033)

Authors: Claire E. Lewis | Allison S. Harney | Jeffrey W. Pollard

https://doi.org/10.1016/j.ccell.2016.05.017 Actions

Selective estrogen receptor modulation

JOURNAL ARTICLE published March 2004 in Cancer Cell

Authors: V.Craig Jordan

https://doi.org/10.1016/s1535-6108(04)00059-5 Actions

Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

JOURNAL ARTICLE published May 2020 in Cancer Cell

Authors: Wendy Béguelin | Matt Teater | Cem Meydan | Kenneth B. Hoehn | Jude M. Phillip | Alexey A. Soshnev | Leandro Venturutti | Martín A. Rivas | María T. Calvo-Fernández | Johana Gutierrez | Jeannie M. Camarillo | Katsuyoshi Takata | Karin Tarte | Neil L. Kelleher | Christian Steidl | Christopher E. Mason | Olivier Elemento | C. David Allis | Steven H. Kleinstein | Ari M. Melnick

https://doi.org/10.1016/j.ccell.2020.04.004 Actions

Radiotherapy Complements Immune Checkpoint Blockade

JOURNAL ARTICLE published April 2015 in Cancer Cell

Authors: Shin Foong Ngiow | Grant A. McArthur | Mark J. Smyth

https://doi.org/10.1016/j.ccell.2015.03.015 Actions

Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

JOURNAL ARTICLE published November 2011 in Cancer Cell

Authors: Charbel Darido | Smitha R. Georgy | Tomasz Wilanowski | Sebastian Dworkin | Alana Auden | Quan Zhao | Gerhard Rank | Seema Srivastava | Moira J. Finlay | Anthony T. Papenfuss | Pier Paolo Pandolfi | Richard B. Pearson | Stephen M. Jane

https://doi.org/10.1016/j.ccr.2011.10.014 Actions

The tumor-suppressive functions of the human INK4A locus

JOURNAL ARTICLE published October 2003 in Cancer Cell

Authors: P.Mathijs Voorhoeve | Reuven Agami

https://doi.org/10.1016/s1535-6108(03)00223-x Actions

IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer

JOURNAL ARTICLE published September 2008 in Cancer Cell

Authors: Bigang Liu | Xiaojun Xia | Feng Zhu | Eunmi Park | Steve Carbajal | Kaoru Kiguchi | John DiGiovanni | Susan M. Fischer | Yinling Hu

https://doi.org/10.1016/j.ccr.2008.07.017 Actions
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